{"id":192,"date":"2024-05-31T14:43:47","date_gmt":"2024-05-31T14:43:47","guid":{"rendered":"https:\/\/novaptech.com\/?page_id=192"},"modified":"2025-02-28T12:58:22","modified_gmt":"2025-02-28T12:58:22","slug":"aptamers-vs-antibodies-advantages","status":"publish","type":"page","link":"https:\/\/novaptech.com\/fr\/aptamers-vs-antibodies-advantages\/","title":{"rendered":"Aptam\u00e8res vs anticorps | Novaptech"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"192\" class=\"elementor elementor-192\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8de3f03 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"8de3f03\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1c21df4 elementor-widget elementor-widget-spacer\" data-id=\"1c21df4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3b72ad9 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"3b72ad9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4261003 elementor-widget elementor-widget-heading\" data-id=\"4261003\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Aptam\u00e8res et anticorps <br> \nDiff\u00e9rences et Avantages<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-acc92b1 elementor-widget elementor-widget-text-editor\" data-id=\"acc92b1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Les aptam\u00e8res et les anticorps sont deux outils majeurs qui ont r\u00e9volutionn\u00e9 notre approche de l'analyse, du diagnostic, du traitement et de la recherche.<br \/>Les aptam\u00e8res sont de petites mol\u00e9cules constitu\u00e9es d'ADN ou d'ARN, con\u00e7ues in vitro pour se lier de mani\u00e8re hautement sp\u00e9cifique \u00e0 une cible donn\u00e9e, qu'il s'agisse de prot\u00e9ines, de virus, de bact\u00e9ries, de cellules eucaryotes, de m\u00e9dicaments ou d'autres compos\u00e9s chimiques.<br \/>Les anticorps, quant \u00e0 eux, sont des prot\u00e9ines naturellement produites par le syst\u00e8me immunitaire en r\u00e9ponse \u00e0 la pr\u00e9sence d'antig\u00e8nes \u00e9trangers, tels que des bact\u00e9ries ou des virus.<br \/>Ces prot\u00e9ines ont la capacit\u00e9 de reconna\u00eetre et de neutraliser sp\u00e9cifiquement ces antig\u00e8nes, ce qui en fait des acteurs cl\u00e9s de la r\u00e9ponse immunitaire de l'organisme.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-da2156e e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"da2156e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3b76778 elementor-widget elementor-widget-text-editor\" data-id=\"3b76778\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\"><span style=\"color: #575454;\">D\u00e9couvrez le potentiel <a href=\"https:\/\/novaptech.com\/fr\/what-are-aptamers-selex\/\"><span style=\"color: #923393;\">aptamers<\/span><\/a> et leurs avantages en comparant <\/span>aptamers vs antibodies.<span style=\"color: #575454;\"> Explorez  les m\u00e9thodes d' <span style=\"color: #923393;\"><a style=\"color: #923393;\" href=\"https:\/\/novaptech.com\/fr\/biomarker-analysis\/\" target=\"_new\" rel=\"noreferrer\">analyse des biomarqueurs<\/a> <\/span>et d\u00e9couvrez les recherches de pointe men\u00e9es dans notre <span style=\"color: #923393;\"><a style=\"color: #923393;\" href=\"https:\/\/novaptech.com\/fr\/biomarker-analysis-novaptech-2\/\" rel=\"noreferrer\">laboratoire de biotechnologie<\/a><\/span> ainsi que les techniques innovantes d\u2019analyse <a style=\"color: #923393;\" href=\"https:\/\/novaptech.com\/fr\/biomarker-discovery\/\" target=\"_new\" rel=\"noreferrer\">biomarqueurs <\/a>.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-62ee8832 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"62ee8832\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7966e662 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"7966e662\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6d337f9a elementor-widget elementor-widget-heading\" data-id=\"6d337f9a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Aptam\u00e8res et anticorps<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-201d6162 elementor-widget elementor-widget-heading\" data-id=\"201d6162\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Principaux avantages des aptam\u00e8res par rapport aux anticorps<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-00368cb elementor-widget elementor-widget-text-editor\" data-id=\"00368cb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0Les aptam\u00e8res sont des mol\u00e9cules synth\u00e9tiques pouvant \u00eatre d\u00e9velopp\u00e9es contre tout type de cible, y compris des mol\u00e9cules toxiques ou non immunog\u00e8nes. Leur affinit\u00e9 pour leurs cibles est comparable, voire sup\u00e9rieure, \u00e0 celle des anticorps. Ils sont dix fois plus petits que les anticorps et peuvent \u00eatre modifi\u00e9s chimiquement de mani\u00e8re d\u00e9finie et pr\u00e9cise. Ils se conservent et se transportent facilement, tout en pouvant \u00eatre d\u00e9natur\u00e9s par la chaleur de fa\u00e7on r\u00e9versible puis renatur\u00e9s. Leur approvisionnement est assur\u00e9 avec une reproductibilit\u00e9 totale des synth\u00e8ses d\u2019un lot \u00e0 l\u2019autre.<\/p><p>Ils peuvent \u00eatre utilis\u00e9s dans des conditions non physiologiques \u00e0 des fins analytiques. Ils sont non immunog\u00e8nes et peuvent \u00eatre utilis\u00e9s <em>in vivo<\/em>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-654a46fe e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"654a46fe\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-52f5b22 elementor-arrows-position-inside elementor-widget elementor-widget-image-carousel\" data-id=\"52f5b22\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;slides_to_show&quot;:&quot;1&quot;,&quot;navigation&quot;:&quot;arrows&quot;,&quot;autoplay&quot;:&quot;yes&quot;,&quot;pause_on_hover&quot;:&quot;yes&quot;,&quot;pause_on_interaction&quot;:&quot;yes&quot;,&quot;autoplay_speed&quot;:5000,&quot;infinite&quot;:&quot;yes&quot;,&quot;effect&quot;:&quot;slide&quot;,&quot;speed&quot;:500}\" data-widget_type=\"image-carousel.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-image-carousel-wrapper swiper\" role=\"region\" aria-roledescription=\"carousel\" aria-label=\"Image Carousel\" dir=\"ltr\">\n\t\t\t<div class=\"elementor-image-carousel swiper-wrapper\" aria-live=\"off\">\n\t\t\t\t\t\t\t\t<div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"1 sur 1\" data-no-translation-aria-label=\"\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/thumb_600_400_0_0_crop-1.jpg\" alt=\"Aptamers vs antibodies\" \/><\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8c1dda4 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"8c1dda4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/novaptech.com\/fr\/aptamer-services-aptamer-development-optimization\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Les services aptam\u00e8res de Novaptech<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-16af354 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"16af354\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3c0a4df elementor-widget elementor-widget-heading\" data-id=\"3c0a4df\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Avantages des Aptam\u00e8res : en bref<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3e20a93 e-grid e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"3e20a93\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c3a7fa0 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"c3a7fa0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5fdfce7 elementor-widget elementor-widget-image\" data-id=\"5fdfce7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"80\" height=\"80\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/any-target-aptamers-vs-antibodies-advantages-80x80-1.png\" class=\"attachment-large size-large wp-image-226\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fc9c2f9 elementor-widget elementor-widget-heading\" data-id=\"fc9c2f9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Toute cible<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c1108a4 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"c1108a4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-69399aa elementor-widget elementor-widget-image\" data-id=\"69399aa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"80\" height=\"80\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/tissue-penetration-aptamers-vs-antibodies-advantages-80x80-1.png\" class=\"attachment-large size-large wp-image-229\" alt=\"Biomarker analysis\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6afeffa elementor-widget elementor-widget-heading\" data-id=\"6afeffa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">P\u00e9n\u00e9tration cellulaire<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0c9fa3d e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"0c9fa3d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4a3c086 elementor-widget elementor-widget-image\" data-id=\"4a3c086\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"80\" height=\"80\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/superior-affinity-and-specificity-aptamers-vs-antibodies-advantages-80x80-1.png\" class=\"attachment-large size-large wp-image-228\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0ef1827 elementor-widget elementor-widget-heading\" data-id=\"0ef1827\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Haute affinit\u00e9 et sp\u00e9cificit\u00e9<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-40899b9 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"40899b9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-463f5cd elementor-widget elementor-widget-image\" data-id=\"463f5cd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"80\" height=\"80\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/scalable-production-aptamers-vs-antibodies-advantages-80x80-1.png\" class=\"attachment-large size-large wp-image-227\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a88baab elementor-widget elementor-widget-heading\" data-id=\"a88baab\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Production \u00e0 grande \u00e9chelle<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-45b611b e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"45b611b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b845757 elementor-widget elementor-widget-heading\" data-id=\"b845757\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Aptam\u00e8res vs anticorps: en d\u00e9tails<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2bbe0d7 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"2bbe0d7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dfe8a5d elementor-widget-mobile__width-auto eael-dt-th-align-center eael-table-align-center elementor-widget elementor-widget-eael-data-table\" data-id=\"dfe8a5d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-data-table.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"eael-data-table-wrap\" data-table_id=\"dfe8a5d\" id=\"eael-data-table-wrapper-dfe8a5d\" data-custom_responsive=\"false\">\n\t\t\t<table class=\"tablesorter eael-data-table center\" id=\"eael-data-table-dfe8a5d\">\n\t\t\t    <thead>\n\t\t\t        <tr class=\"table-header\">\n\t\t\t\t\t\t\t\t\t            <th class=\"\" id=\"\" colspan=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"data-table-header-text\"><\/span><\/th>\n\t\t\t        \t\t\t\t            <th class=\"\" id=\"\" colspan=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"data-table-header-text\">Anticorps monoclonal<\/span><\/th>\n\t\t\t        \t\t\t\t            <th class=\"\" id=\"\" colspan=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"data-table-header-text\">La s\u00e9lection d'aptam\u00e8re<\/span><\/th>\n\t\t\t        \t\t\t\t        <\/tr>\n\t\t\t    <\/thead>\n\t\t\t  \t<tbody>\n\t\t\t\t\t\t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tStabilit\u00e9\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Sensibles \u00e0 la temp\u00e9rature, les anticorps n\u00e9cessitent une r\u00e9frig\u00e9ration. La d\u00e9naturation est irr\u00e9versible<\/p>\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tStables \u00e0 temp\u00e9rature ambiante, les aptam\u00e8res ont une dur\u00e9e de conservation longue. La d\u00e9naturation est r\u00e9versible\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/tr>\n\t\t\t        \t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tTaille\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p style=\"text-align: left\">Grosses mol\u00e9cules (\u223c 160 kDa), r\u00e9sistent \u00e0 la filtration par les reins<\/p>\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tPetites mol\u00e9cules (10-20 kDa) assurant une interaction optimis\u00e9e avec leur cible et une diffusion rapide dans des environnements \u00e0 acc\u00e8s restreint\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/tr>\n\t\t\t        \t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tProcessus de d\u00e9veloppement\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tN\u00e9cessite une r\u00e9ponse immunitaire et du mat\u00e9riel vivant (animaux, cellules)\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tS\u00e9lectionn\u00e9 in vitro par une m\u00e9thode pouvant inclure des \u00e9tapes de s\u00e9lection positive et n\u00e9gative, garantissant ainsi une tr\u00e8s haute sp\u00e9cificit\u00e9. Seules quelques nanomoles de la cible sont n\u00e9cessaires \u00e0 la s\u00e9lection. Une grande diversit\u00e9 mol\u00e9culaire est cribl\u00e9e\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/tr>\n\t\t\t        \t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tCible potentielle\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tLes cibles doivent produire une r\u00e9ponse immunitaire\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tPeut se lier \u00e0 de tr\u00e8s petites cibles toxiques, non immunog\u00e8nes\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/tr>\n\t\t\t        \t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tTemps et co\u00fbt de production\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tEn plusieurs mois \/ La production d\u2019anticorps n\u00e9cessite des proc\u00e9dures in vivo longues et co\u00fbteuses\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t   \t\t\t\t\t\t\t\t\t\t\t<td colspan=\"\" rowspan=\"\" class=\"\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"td-content-wrapper\"><div class=\"td-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tEn quelques semaines \/ Les aptam\u00e8res s\u00e9lectionn\u00e9s sont synth\u00e9tis\u00e9s chimiquement, r\u00e9duisant ainsi le co\u00fbt de production\t\t\t\t\t\t\t\t\t\t\t\t<\/div><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/tr>\n\t\t\t        \t\t\t    <\/tbody>\n\t\t\t<\/table>\n\t\t<\/div>\n\t  \t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7706fb68 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"7706fb68\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5c01ddf9 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"5c01ddf9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4cc5b768 elementor-widget elementor-widget-heading\" data-id=\"4cc5b768\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Des questions ? Contactez-nous<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5b529810 elementor-widget elementor-widget-heading\" data-id=\"5b529810\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Vous avez une question sur la s\u00e9lection d\u2019aptam\u00e8res ou le d\u00e9veloppement de tests ?\nVeuillez remplir le formulaire ci-dessous en d\u00e9taillant votre demande afin que nous puissions vous apporter une r\u00e9ponse pr\u00e9cise. Un appel t\u00e9l\u00e9phonique ou une visioconf\u00e9rence peut \u00eatre organis\u00e9(e) si n\u00e9cessaire, et un accord de confidentialit\u00e9 peut \u00eatre sign\u00e9 sur demande. Nous nous engageons \u00e0 vous r\u00e9pondre dans les plus brefs d\u00e9lais (g\u00e9n\u00e9ralement moins de 2 jours ouvr\u00e9s).<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6f6e31c7 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"6f6e31c7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-154bf021 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"154bf021\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/novaptech.com\/fr\/contact-us-aptamer-company-france-eu\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Contactez-nous<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7b14de16 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"7b14de16\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-43fb511c elementor-widget elementor-widget-image\" data-id=\"43fb511c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"337\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/thumb_600_0_0_0_auto-2.jpg\" class=\"attachment-full size-full wp-image-183\" alt=\"Biomarker analysis\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/thumb_600_0_0_0_auto-2.jpg 600w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/thumb_600_0_0_0_auto-2-300x169.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-198823d5 elementor-widget elementor-widget-heading\" data-id=\"198823d5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Votre contact scientifique :<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f9adf99 elementor-widget elementor-widget-heading\" data-id=\"5f9adf99\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Jean-Jacques Toulm\u00e9, PhD, CSO<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-51877a8 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"51877a8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c4a4596 elementor-widget elementor-widget-toggle\" data-id=\"c4a4596\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-2061\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-2061\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><svg class=\"e-font-icon-svg e-fas-caret-right\" viewbox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><svg class=\"elementor-toggle-icon-opened e-font-icon-svg e-fas-caret-up\" viewbox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M288.662 352H31.338c-17.818 0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">L'importance des aptam\u00e8res et des anticorps dans les applications diagnostiques \net analytiques<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-2061\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-2061\"><p style=\"text-align: left;\" class=\"translation-block\">Les aptam\u00e8res et les anticorps jouent un r\u00f4le central dans les diagnostics et les analyses. Leurs \nsp\u00e9cificit\u00e9s de liaison \u00e9lev\u00e9es en font des outils de choix pour la d\u00e9tection quantitative de cibles \nmol\u00e9culaires dans divers \u00e9chantillons (tissus, sang, eau, aliments,...). \nIls sont largement utilis\u00e9s pour la biod\u00e9tection en association avec diff\u00e9rentes modalit\u00e9s de \ntransduction du signal (fluorescence, colorim\u00e9trie, \u00e9lectrochimie). \nIls permettent la d\u00e9tection quantitative sp\u00e9cifique de la mol\u00e9cule cible sur le terrain gr\u00e2ce \u00e0 des \ntests simples, bon march\u00e9 et rapides.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-2062\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"button\" aria-controls=\"elementor-tab-content-2062\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><svg class=\"e-font-icon-svg e-fas-caret-right\" viewbox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><svg class=\"elementor-toggle-icon-opened e-font-icon-svg e-fas-caret-up\" viewbox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M288.662 352H31.338c-17.818 0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">L'importance des aptam\u00e8res et des anticorps dans la recherche et la m\u00e9decine<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-2062\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"region\" aria-labelledby=\"elementor-tab-title-2062\"><p class=\"translation-block\">Les aptam\u00e8res et les anticorps jouent un r\u00f4le central dans la recherche biom\u00e9dicale et la pratique \nm\u00e9dicale. Leurs sp\u00e9cificit\u00e9s de liaison \u00e9lev\u00e9es en font des outils de choix pour la d\u00e9tection et \nl'identification de cibles mol\u00e9culaires sp\u00e9cifiques dans les \u00e9chantillons biologiques. \nIls sont largement utilis\u00e9s dans les tests de diagnostic, la d\u00e9couverte de biomarqueurs, la \ncaract\u00e9risation des prot\u00e9ines et la compr\u00e9hension des m\u00e9canismes sous-jacents aux maladies. \nEn m\u00e9decine, les anticorps monoclonaux sont utilis\u00e9s pour traiter certaines maladies autoimmunes et certains types de cancer. Les aptam\u00e8res, quant \u00e0 eux, offrent une alternative \nprometteuse, notamment en tant que vecteurs de m\u00e9dicaments cibl\u00e9s et de m\u00e9decine \npersonnalis\u00e9e.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-2063\" class=\"elementor-tab-title\" data-tab=\"3\" role=\"button\" aria-controls=\"elementor-tab-content-2063\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><svg class=\"e-font-icon-svg e-fas-caret-right\" viewbox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><svg class=\"elementor-toggle-icon-opened e-font-icon-svg e-fas-caret-up\" viewbox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M288.662 352H31.338c-17.818 0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">Sp\u00e9cificit\u00e9s des aptam\u00e8res<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-2063\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"region\" aria-labelledby=\"elementor-tab-title-2063\"><p class=\"translation-block\">Le processus de s\u00e9lection des aptam\u00e8res, ou SELEX, est au c\u0153ur de l'identification des \naptam\u00e8res sp\u00e9cifiques. Il commence par la synth\u00e8se d'une biblioth\u00e8que al\u00e9atoire \nd'oligonucl\u00e9otides dans laquelle chaque s\u00e9quence poss\u00e8de une structure tridimensionnelle \nunique.<\/p><p><strong>M\u00e9canisme de liaison sp\u00e9cifique<\/strong><\/p><p class=\"translation-block\">Les aptam\u00e8res forment des liaisons hydrog\u00e8ne, des interactions \u00e9lectrostatiques et des \ninteractions de Van der Waals avec la cible. Cela permet une liaison hautement sp\u00e9cifique entre \nl'aptam\u00e8re et sa cible, en fonction des caract\u00e9ristiques mol\u00e9culaires pr\u00e9cises de cette derni\u00e8re. \nLa conformation tridimensionnelle de l'aptam\u00e8re est cruciale, lui permettant de s'adapter \nparfaitement \u00e0 la forme de la cible, assurant ainsi la sp\u00e9cificit\u00e9 de la liaison.<\/p><p><strong>Applications dans la recherche et la m\u00e9decine<\/strong><\/p><p>La capacit\u00e9 des aptam\u00e8res \u00e0 se lier sp\u00e9cifiquement \u00e0 des cibles mol\u00e9culaires en fait des outils pr\u00e9cieux pour la d\u00e9tection de biomarqueurs, la caract\u00e9risation des prot\u00e9ines, l'analyse des m\u00e9dicaments et des contaminants, ainsi que pour la compr\u00e9hension des m\u00e9canismes biologiques. Ils sont \u00e9galement utilis\u00e9s pour cibler sp\u00e9cifiquement les cellules tumorales ou les cellules infect\u00e9es par un virus, ouvrant ainsi la voie \u00e0 des possibilit\u00e9s de traitements cibl\u00e9s. En recherche, les aptam\u00e8res sont utilis\u00e9s pour \u00e9tudier les interactions prot\u00e9iques, identifier les partenaires de liaison et explorer les r\u00e9seaux de signalisation cellulaire..<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-2064\" class=\"elementor-tab-title\" data-tab=\"4\" role=\"button\" aria-controls=\"elementor-tab-content-2064\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><svg class=\"e-font-icon-svg e-fas-caret-right\" viewbox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><svg class=\"elementor-toggle-icon-opened e-font-icon-svg e-fas-caret-up\" viewbox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M288.662 352H31.338c-17.818 0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"> Pourquoi choisir les aptam\u00e8res plut\u00f4t que les anticorps ?<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-2064\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"region\" aria-labelledby=\"elementor-tab-title-2064\"><p>L'un des principaux avantages des aptam\u00e8res par rapport aux anticorps est leur grande sp\u00e9cificit\u00e9. Les aptam\u00e8res sont identifi\u00e9s en laboratoire par des s\u00e9lections positives et n\u00e9gatives afin de discriminer les cibles \u00e9troitement apparent\u00e9es. <br>Le processus de s\u00e9lection SELEX g\u00e9n\u00e8re des aptam\u00e8res qui se lient de mani\u00e8re forte et sp\u00e9cifique \u00e0 la cible, minimisant ainsi les liaisons non sp\u00e9cifiques avec d'autres mol\u00e9cules pr\u00e9sentes dans l'\u00e9chantillon. Cette sp\u00e9cificit\u00e9 garantit une plus grande pr\u00e9cision dans la d\u00e9tection et la quantification des cibles mol\u00e9culaires, tout en r\u00e9duisant le risque de faux positifs et de faux n\u00e9gatifs. <br><span lang=\"EN-US\" style=\"font-size: 12pt; font-family: Arial, sans-serif; color: rgb(51, 51, 51);\">\u00b7&nbsp;<\/span><span style=\"caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-family: -webkit-standard; font-size: medium;\"><\/span>Polyvalence des aptam\u00e8res : Les aptam\u00e8res sont obtenus par synth\u00e8se chimique sur support solide. Des modifications chimiques peuvent \u00eatre introduites \u00e0 volont\u00e9 \u00e0 des sites sp\u00e9cifiques afin de leur conf\u00e9rer des propri\u00e9t\u00e9s suppl\u00e9mentaires en fonction de l'application (augmentation de la dur\u00e9e de vie, d\u00e9tection par fluorescence, immobilisation sur une biochip, \u2026). <br><span lang=\"EN-US\" style=\"font-size: 12pt; font-family: Arial, sans-serif; color: rgb(51, 51, 51);\">\u00b7&nbsp;<\/span><span style=\"caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-family: -webkit-standard; font-size: medium;\"><\/span>Stabilit\u00e9 thermique des aptam\u00e8res : Le chauffage  \u00e0 80-90 \u00b0C des aptam\u00e8res entraine une d\u00e9naturation.. <br>Cependant, contrairement aux prot\u00e9ines, ils se renaturent lors du refroidissement et retrouvent leur fonctionnalit\u00e9.<\/p>\n<p><strong>Avantage des aptam\u00e8res en termes de co\u00fbts<\/strong><\/p>\n<p class=\"translation-block\">La production \u00e0 grande \u00e9chelle d'anticorps monoclonaux n\u00e9cessite le d\u00e9veloppement et \nl'entretien de lign\u00e9es cellulaires hybrides, ce qui est extr\u00eamement co\u00fbteux. De plus, la \nproduction d'anticorps n\u00e9cessite des installations sp\u00e9cialis\u00e9es et donc un investissement \nimportant en ressources mat\u00e9rielles.<\/p>\n<p class=\"translation-block\">En revanche, en termes de co\u00fbts de production, les aptam\u00e8res pr\u00e9sentent un avantage significatif \npar rapport aux anticorps. De plus, la synth\u00e8se chimique des aptam\u00e8res, y compris dans des \nconditions BPF, garantit un approvisionnement sans variabilit\u00e9 de lot.<\/p>\n<p><strong> Notre partenariat avec Eurogentec<\/strong><\/p>\n<p class=\"translation-block\">Eurogentec fournit des produits et des services d'oligonucl\u00e9otides aux scientifiques impliqu\u00e9s \ndans la recherche en sciences de la vie, le diagnostic mol\u00e9culaire et le d\u00e9veloppement \nth\u00e9rapeutique. \nExpert en synth\u00e8se \u00e0 petite et grande \u00e9chelle, Eurogentec produit une large gamme \nd'oligonucl\u00e9otides, y compris des oligonucl\u00e9otides modifi\u00e9s chimiquement (squelettes \nr\u00e9sistants aux nucl\u00e9ases, bases nucl\u00e9iques modifi\u00e9es, s\u00e9quences conjugu\u00e9es \u00e0 une extr\u00e9mit\u00e9, \netc\u2026). \nNovaptech et Eurogentec ont sign\u00e9 un accord de partenariat pour la production d'aptam\u00e8res \ns\u00e9lectionn\u00e9s par Novaptech. <a href=\"https:\/\/www.eurogentec.com\/en\/search?q=novaptech\" target=\"_self\">https:\/\/www.eurogentec.com\/en\/search?q=novaptech<\/a><\/p>\n<p><strong> Faible\/absence d'immunog\u00e9nicit\u00e9 des aptam\u00e8res<\/strong><\/p>\n<p>Un autre avantage majeur dans le match anticorps vs aptam\u00e8re r\u00e9side dans la faible voire \nl'absence d'immunog\u00e9nicit\u00e9 des aptam\u00e8res par rapport aux anticorps.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Aptamers vs antibodies What are the differences and advantages ? Aptamers and antibodies are two major players that have revolutionized the way we approach analysis, diagnosis, treatment and research.Aptamers are small molecules composed of DNA or RNA that are engineered in the laboratory to bind highly specifically to a given target, whether proteins, viruses, bacteria, eukaryotic cells, drugs or other chemical compounds.Antibodies are proteins produced naturally by the immune system in response to the presence of antigens, such as bacteria or viruses.These proteins have the ability to specifically recognize and neutralize these antigens, making them key players in the body&#8217;s immune response. Discover the potential of aptamers and their advantages in the debate of aptamers vs antibodies. Learn about the methods of biomarker analysis and explore the advanced research conducted in our biotechnology laboratory and the innovative approaches to biomarker analysis. Aptamers vs antibodies Key advantages of aptamers over antibodies \u00a0Aptamers are synthetic molecules that can be raised against any kind of target, including toxic or non-immunogenic ones. They bind their target with affinity similar or higher than antibodies. They are 10 fold smaller than antibodies and can be chemically-modified at will in a defined and precise way. They can be easily stored and delivered ; they can be reversibly heat-denatured and renatured. The sourcing is guaranteed with a total batch to batch reproducibility. They can be used under non physiological conditions for analytical purposes. They are non\u2013immunogenic and can be used in vivo. Novaptech&#8217;s aptamer services Advantages of Aptamers : in short Any target Tissue penetration Superior affinity &amp; specificity Scalable production Aptamers vs antibodies : in details Monoclonal antibody Aptamer Stability Sensitive to temperature, antibodies require refrigeration. The denaturation is irreversible Stable at room temperature, aptamers have longer shelf life. The denaturation is reversible Size Large molecules (\u223c 160 kDa), resist to filtration by the kidneys Small molecules (10-20 kDa) that display better access to their target Development process Require immune response and animals Selected in vitro by a method that might include positive and negative selection steps, thus ensuring very high specificity. Only a few nanomoles are a few nanomoles of target are required for selection. A large molecular diversity is screened Target potential Targets must produce an immune response Can bind to very small, non-immunogenic, toxic targets Production time and cost In several months \/ The production of antibodies requires long and expensive in vivo procedures In several weeks \/ The selected aptamers are chemically synthetized, reducing the production cost Any question ? Contact us Any question about selection service or assay development ? Please fill in the form below with relevant details for helping us providing an informative answer. Telephone or video call can be arranged. NDA can be signed, would you wish so. We will answer you as quickly as possible (generally less than 2 working days). Contact us Your scientific contact : Jean-Jacques Toulm\u00e9, PhD, CSO The importance of aptamers and antibodies in diagnostics and analytical applications Aptamers and antibodies play a central role in diagnostics and analytical assays. Their high binding specificities make them tools of choice for quantitatively detecting molecular targets in various samples (tissue, blood, water, food,\u2026). They are widely used for biosensing in association with different modalities of signal transduction (fluorescence, colorimetry, electrochemistry). They enable the quantitative specific detection of the target molecule in the field through simple, cheap and rapid assays. The importance of aptamers and antibodies in research and medicine Aptamers and antibodies play a central role in biomedical research and medical practice. Their high binding specificities make them tools of choice for detecting and identifying specific molecular targets in biological samples.They are widely used in diagnostic tests, biomarker discovery, protein characterization and understanding the mechanisms underlying disease. In medicine, monoclonal antibodies are used to treat certain autoimmune diseases and certain types of cancer. Aptamers, on the other hand, offer a promising alternative, notably as vectors for targeted drugs and personalized medicine. Specific features of aptamers The aptamer selection process, or SELEX, lies at the heart of the identification of specific aptamers. It begins with the synthesis of a random oligonucleotide library in which each sequence has a unique three-dimensional structure. This library is then subjected to selection cycles that include binding to the target, washing to remove unbound sequences and recovery of target-bound aptamers. This process is repeated many times until aptamers with high specificity and affinity for the target are selected. Specific binding mechanism Aptamers form hydrogen bonds, electrostatic interactions and Van der Waals interactions with the target. This enables highly specific binding between the aptamer and its target, depending on the latter&#8217;s precise molecular characteristics. The three-dimensional conformation of the aptamer is crucial, enabling it to adapt perfectly to the shape of the target, thus providing the specificity of the binding. Applications in research and medicine The ability of aptamers to bind specifically to molecular targets makes them valuable tools for biomarker detection, protein characterization, drug and contaminant analysis and the understanding of biological mechanisms. They are also used to specifically target tumor cells or virus-infected cells, paving the way for targeted treatment possibilities. In research, aptamers are used to study protein interactions, identify binding partners and explore cell signaling networks Why choose aptamers over antibodies ? One of the major advantages of aptamers over antibodies is their high specificity. Aptamers are identified in the laboratory through positive and negative screening in order to discriminate between closely related targets. The SELEX selection process generates aptamers that bind tightly and specifically to the target, minimizing non-specific binding to other molecules in the sample. This specificity guarantees greater precision in the detection and quantification of molecular targets, and reduces the risk of false positives and false negatives. \u00b7&nbsp;Versatility of aptamers : Aptamers are obtained by chemical synthesis on solid support. Chemical modifications can be introduced at will at given sites in order to provide them with additional properties depending on the application (increased lifetime, detection by fluorescence, immobilization on a biochip, \u2026). \u00b7&nbsp;Thermal stability of<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-192","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Aptamers vs Antibodies | Novaptech - Novaptech<\/title>\n<meta name=\"description\" content=\"Aptamers and antibodies are two major players that have revolutionized the way we approach analysis, diagnosis, treatment and research.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/novaptech.com\/fr\/aptamers-vs-antibodies-advantages\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Aptamers vs Antibodies | Novaptech - 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