{"id":326,"date":"2024-06-01T12:49:24","date_gmt":"2024-06-01T12:49:24","guid":{"rendered":"https:\/\/novaptech.com\/?page_id=326"},"modified":"2024-07-28T13:23:28","modified_gmt":"2024-07-28T13:23:28","slug":"second-generation-aptamers-selkiss-aptaswitch","status":"publish","type":"page","link":"https:\/\/novaptech.com\/fr\/second-generation-aptamers-selkiss-aptaswitch\/","title":{"rendered":"Novatech structure switching aptamers"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"326\" class=\"elementor elementor-326\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7dc87abd e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"7dc87abd\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-206a8c99 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"206a8c99\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2b7a0202 elementor-widget elementor-widget-heading\" data-id=\"2b7a0202\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Aptam\u00e8res \u00e0 commutation de structure Novaptech<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4dcbbe0d elementor-widget elementor-widget-heading\" data-id=\"4dcbbe0d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Technologie Novaptech Aptaswich &amp; NOVAswitch<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-24b16c4d elementor-widget elementor-widget-heading\" data-id=\"24b16c4d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<p class=\"elementor-heading-title elementor-size-default\">On sait que les aptam\u00e8res subissent g\u00e9n\u00e9ralement un changement de conformation lors de leur liaison \u00e0 leur ligand. Ceci peut \u00eatre exploit\u00e9 pour signaler la pr\u00e9sence de la cible. Le changement structurel est alors associ\u00e9 \u00e0 un signal (transfert d'\u00e9nergie de fluorescence par exemple). Ceci peut \u00eatre d\u00e9lib\u00e9r\u00e9ment exploit\u00e9 pour la conception de biocapteurs \u00e0 base d\u2019aptam\u00e8res.<\/p>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6d856f8 elementor-align-left elementor-widget elementor-widget-button\" data-id=\"6d856f8\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/novaptech.com\/fr\/contact-us-aptamer-company-france-eu\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Parlez-nous de votre test<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-660eac06 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"660eac06\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5fa2a741 elementor-widget elementor-widget-image\" data-id=\"5fa2a741\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"400\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_600_0_0_0_auto.jpg\" class=\"attachment-large size-large wp-image-331\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_600_0_0_0_auto.jpg 600w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_600_0_0_0_auto-300x200.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-89e1256 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"89e1256\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-11e51a9 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"11e51a9\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ec6579a elementor-widget elementor-widget-image\" data-id=\"ec6579a\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"600\" height=\"400\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_600_0_0_0_auto-1.jpg\" class=\"attachment-large size-large wp-image-341\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_600_0_0_0_auto-1.jpg 600w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_600_0_0_0_auto-1-300x200.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7aa026f e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"7aa026f\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4e52eaf elementor-widget elementor-widget-heading\" data-id=\"4e52eaf\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Aptaswitch<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-76549eb elementor-widget elementor-widget-heading\" data-id=\"76549eb\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Les aptam\u00e8res \u00e0 commutation de structure Novaptech profitent des interactions dites de baiser. Les complexes boucle-boucle ou \u00ab baiser \u00bb impliquent la formation d\u2019un court double brin entre les boucles apicales compl\u00e9mentaires des \u00e9pingles \u00e0 cheveux d\u2019acide nucl\u00e9ique. L'aptam\u00e8re bascule entre une forme en \u00e9pingle \u00e0 cheveux ouverte et ferm\u00e9e en l'absence et en pr\u00e9sence de son ligand apparent\u00e9, respectivement. Sous sa forme ferm\u00e9e, l'aptaswitch est reconnu par une autre \u00e9pingle \u00e0 cheveux nomm\u00e9e aptakiss gr\u00e2ce \u00e0 l'interaction par baiser. L'aptakiss ne se lie pas \u00e0 l'aptaswitch ouvert. Par cons\u00e9quent, le complexe aptakiss-aptaswitch signale la pr\u00e9sence de la cible.<\/p>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a3f087 elementor-align-left elementor-widget elementor-widget-button\" data-id=\"2a3f087\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/16-durand-nar.pdf\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Voir le document<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-235fc27 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"235fc27\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2b2af0e e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"2b2af0e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0014846 elementor-widget elementor-widget-heading\" data-id=\"0014846\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">NOVAswitch<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-004eec3 elementor-widget elementor-widget-heading\" data-id=\"004eec3\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Les interactions de baiser sont utilis\u00e9es pour effectuer la s\u00e9lection dans la proc\u00e9dure Novaptech NOVAswitch. La s\u00e9lection est effectu\u00e9e contre des mol\u00e9cules libres en solution. Les candidats s\u00e9lectionn\u00e9s sont des aptaswitches fonctionnels int\u00e9grables dans des biocapteurs.<\/p>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-245d624 elementor-align-left elementor-widget elementor-widget-button\" data-id=\"245d624\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/novaptech.com\/fr\/rapid-field-tests-pollutants-drug-residues\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">D\u00e9couvrez notre programme R&amp;D pour les tests rapides et multiplexes<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-17147e6 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"17147e6\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e89e81b elementor-widget elementor-widget-image\" data-id=\"e89e81b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"600\" height=\"322\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_600_0_0_0_auto.png\" class=\"attachment-large size-large wp-image-348\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_600_0_0_0_auto.png 600w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_600_0_0_0_auto-300x161.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-97654c5 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"97654c5\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f88d537 elementor-widget elementor-widget-heading\" data-id=\"f88d537\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Tests bas\u00e9s sur Aptaswitch<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1d8dc6b4 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"1d8dc6b4\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-35058b91 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"35058b91\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-eafd2ac elementor-widget elementor-widget-video\" data-id=\"eafd2ac\" data-element_type=\"widget\" data-settings=\"{&quot;video_type&quot;:&quot;vimeo&quot;,&quot;show_image_overlay&quot;:&quot;yes&quot;,&quot;image_overlay&quot;:{&quot;url&quot;:&quot;https:\\\/\\\/novaptech-com.preview-domain.com\\\/wp-content\\\/uploads\\\/2024\\\/06\\\/thumb_348_196_0_0_crop.png&quot;,&quot;id&quot;:294,&quot;size&quot;:&quot;&quot;,&quot;alt&quot;:&quot;&quot;,&quot;source&quot;:&quot;library&quot;}}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<iframe class=\"elementor-video-iframe\" allowfullscreen allow=\"clipboard-write\" title=\"Lecteur vid\u00e9o vimeo\" src=\"https:\/\/player.vimeo.com\/video\/267761524?color&amp;autopause=0&amp;loop=0&amp;muted=0&amp;title=1&amp;portrait=1&amp;byline=1#t=\"><\/iframe>\t\t\t\t<div class=\"elementor-custom-embed-image-overlay\" style=\"background-image: url(https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop.png);\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-custom-embed-play\" role=\"button\" aria-label=\"Lire la vid\u00e9o\" tabindex=\"0\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-eicon-play\" viewbox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M838 162C746 71 633 25 500 25 371 25 258 71 163 162 71 254 25 367 25 500 25 633 71 746 163 837 254 929 367 979 500 979 633 979 746 933 838 837 929 746 975 633 975 500 975 367 929 254 838 162M808 192C892 279 933 379 933 500 933 621 892 725 808 808 725 892 621 938 500 938 379 938 279 896 196 808 113 725 67 621 67 500 67 379 108 279 196 192 279 108 383 62 500 62 621 62 721 108 808 192M438 392V642L642 517 438 392Z\"><\/path><\/svg>\t\t\t\t\t\t\t<span class=\"elementor-screen-only\">Lire la vid\u00e9o<\/span>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4569d06a elementor-widget elementor-widget-heading\" data-id=\"4569d06a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Tests rapides<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6f4959df e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"6f4959df\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2b0acb2f elementor-widget elementor-widget-image\" data-id=\"2b0acb2f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/novaptech.com\/fr\/portfolio_page\/aptamer-lateral-flow-assays\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"348\" height=\"196\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop-6.jpg\" class=\"attachment-large size-large wp-image-363\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop-6.jpg 348w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop-6-300x169.jpg 300w\" sizes=\"(max-width: 348px) 100vw, 348px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1a04dbc8 elementor-widget elementor-widget-heading\" data-id=\"1a04dbc8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Test bandelette <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7a258799 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"7a258799\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-257faeb3 elementor-widget elementor-widget-image\" data-id=\"257faeb3\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/novaptech.com\/fr\/second-generation-aptamers-selkiss-aptaswitch\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"348\" height=\"196\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop-1-1.jpg\" class=\"attachment-large size-large wp-image-361\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop-1-1.jpg 348w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop-1-1-300x169.jpg 300w\" sizes=\"(max-width: 348px) 100vw, 348px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2eded7cf elementor-widget elementor-widget-heading\" data-id=\"2eded7cf\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Environment &amp; food safety monitoring\n<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f60eb25 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"f60eb25\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-41e1fce elementor-widget elementor-widget-image\" data-id=\"41e1fce\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/novaptech.com\/fr\/second-generation-aptamers-selkiss-aptaswitch\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"348\" height=\"196\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop-2.jpg\" class=\"attachment-large size-large wp-image-362\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop-2.jpg 348w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/thumb_348_196_0_0_crop-2-300x169.jpg 300w\" sizes=\"(max-width: 348px) 100vw, 348px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-932b5e4 elementor-widget elementor-widget-heading\" data-id=\"932b5e4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">D\u00e9tection d'un m\u00e9dicament dans des fluides biologiques\n<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3a623ed e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"3a623ed\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d8cd2c8 elementor-widget elementor-widget-heading\" data-id=\"d8cd2c8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Ils soutiennent notre R&amp;D<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b580d6e e-grid e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"b580d6e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-89eff04 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"89eff04\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d2ddd3d elementor-widget elementor-widget-image\" data-id=\"d2ddd3d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.nouvelle-aquitaine.fr\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-region-nouvelle-aquitaine.jpg\" class=\"attachment-large size-large wp-image-125\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-region-nouvelle-aquitaine.jpg 500w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-region-nouvelle-aquitaine-300x300.jpg 300w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-region-nouvelle-aquitaine-150x150.jpg 150w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-56d77c1 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"56d77c1\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7a1ae8 elementor-widget elementor-widget-image\" data-id=\"c7a1ae8\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"http:\/\/www.bordeauxunitec.com\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"800\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-unitec.png\" class=\"attachment-large size-large wp-image-126\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-unitec.png 1000w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-unitec-300x300.png 300w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-unitec-150x150.png 150w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-unitec-768x768.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0cf75b3 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"0cf75b3\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c8edfc0 elementor-widget elementor-widget-image\" data-id=\"c8edfc0\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"http:\/\/www.aquiti.fr\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-aquiti.jpg\" class=\"attachment-large size-large wp-image-122\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-aquiti.jpg 300w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-aquiti-150x150.jpg 150w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7f59177 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"7f59177\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2671812 elementor-widget elementor-widget-image\" data-id=\"2671812\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.bpifrance.fr\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-bpi-france.jpg\" class=\"attachment-large size-large wp-image-123\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-bpi-france.jpg 500w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-bpi-france-300x300.jpg 300w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-bpi-france-150x150.jpg 150w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c7c11b3 elementor-widget elementor-widget-image\" data-id=\"c7c11b3\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/pole-nsl.org\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-nsl.jpg\" class=\"attachment-large size-large wp-image-124\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-nsl.jpg 500w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-nsl-300x300.jpg 300w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-partners-nsl-150x150.jpg 150w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e375240 elementor-widget elementor-widget-image\" data-id=\"e375240\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.frenchtechbordeaux.com\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"241\" height=\"203\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/french-tech-bordeaux-logo.png\" class=\"attachment-large size-large wp-image-115\" alt=\"\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1866707 elementor-widget elementor-widget-image\" data-id=\"1866707\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/novaptech-com.preview-domain.com\/aptamer-company\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"163\" height=\"123\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-europe.png\" class=\"attachment-large size-large wp-image-120\" alt=\"\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-99a008c elementor-widget elementor-widget-image\" data-id=\"99a008c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/mabanque.bnpparibas\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"320\" height=\"86\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-bnp.png\" class=\"attachment-large size-large wp-image-117\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-bnp.png 320w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/novaptech-bnp-300x81.png 300w\" sizes=\"(max-width: 320px) 100vw, 320px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0d6a1b1 elementor-widget elementor-widget-image\" data-id=\"0d6a1b1\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"http:\/\/www.iecb.u-bordeaux.fr\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"171\" height=\"171\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/IECB.jpg\" class=\"attachment-large size-large wp-image-1312\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/IECB.jpg 171w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/IECB-150x150.jpg 150w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/IECB-12x12.jpg 12w\" sizes=\"(max-width: 171px) 100vw, 171px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9a65761 elementor-widget elementor-widget-image\" data-id=\"9a65761\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.cnrs.fr\/fr\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/Design-sans-titre-34.png\" class=\"attachment-full size-full wp-image-2092\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/Design-sans-titre-34.png 500w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/Design-sans-titre-34-300x300.png 300w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/Design-sans-titre-34-150x150.png 150w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/Design-sans-titre-34-12x12.png 12w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-66226de elementor-widget elementor-widget-image\" data-id=\"66226de\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.inserm.fr\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"200\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/1280px-Inserm.svg_-1024x256.png\" class=\"attachment-large size-large wp-image-2090\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/1280px-Inserm.svg_-1024x256.png 1024w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/1280px-Inserm.svg_-300x75.png 300w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/1280px-Inserm.svg_-768x192.png 768w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/1280px-Inserm.svg_-18x5.png 18w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/07\/1280px-Inserm.svg_.png 1280w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-170bfdd elementor-widget elementor-widget-image\" data-id=\"170bfdd\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.pessac.fr\/-1.html\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"170\" height=\"118\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/pessac.jpg\" class=\"attachment-large size-large wp-image-1316\" alt=\"\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/pessac.jpg 170w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/pessac-18x12.jpg 18w\" sizes=\"(max-width: 170px) 100vw, 170px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ee736d3 elementor-widget elementor-widget-image\" data-id=\"ee736d3\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/arna.cnrs.fr\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"123\" height=\"39\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/06\/ARNA.png\" class=\"attachment-large size-large wp-image-1317\" alt=\"\" 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data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Des questions ? Demandez-nous !<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-56efaa03 elementor-widget elementor-widget-heading\" data-id=\"56efaa03\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Une question sur le service de s\u00e9lection ou le d\u00e9veloppement de tests ? Veuillez remplir le formulaire ci-dessous avec des d\u00e9tails pour nous aider \u00e0 fournir une r\u00e9ponse claire. Un appel t\u00e9l\u00e9phonique peut \u00eatre organis\u00e9. Un accord de confidentialit\u00e9 peut \u00eatre sign\u00e9, si vous le souhaitez. Nous vous r\u00e9pondrons dans les plus brefs d\u00e9lais (g\u00e9n\u00e9ralement moins de 2 jours ouvr\u00e9s).<\/p>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5e485a93 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"5e485a93\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-627820c0 elementor-align-left elementor-widget elementor-widget-button\" data-id=\"627820c0\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/novaptech.com\/fr\/contact-us-aptamer-company-france-eu\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Contactez-nous<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-378f4617 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"378f4617\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-71b14de6 elementor-widget elementor-widget-image\" data-id=\"71b14de6\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"337\" src=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/thumb_600_0_0_0_auto-2.jpg\" class=\"attachment-full size-full wp-image-183\" alt=\"Biomarker analysis\" srcset=\"https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/thumb_600_0_0_0_auto-2.jpg 600w, https:\/\/novaptech.com\/wp-content\/uploads\/2024\/05\/thumb_600_0_0_0_auto-2-300x169.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-380fef0f elementor-widget elementor-widget-heading\" data-id=\"380fef0f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Votre contact scientifique :<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-18eee01e elementor-widget elementor-widget-heading\" data-id=\"18eee01e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Jean-Jacques Toulm\u00e9, PhD, CSO<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Novaptech structure-switching aptamers Novaptech Aptaswich &#038; NOVAswitch technology Aptamers are known to generally undergo a conformational change upon binding to their ligand. This can be exploited for signaling the presence of the target. The structural change is then associated to a signal (fluorescence energy transfer for instance). This can be deliberately exploited for the design of aptamer-based biosensors. Tell us about your assay Aptaswitch Novaptech structure switching aptamers take advantage of so-called kissing interactions. Loop-loop or \u201ckissing\u201d complexes involve the formation of a short double-strand between complementary apical loops of nucleic acid hairpins. The aptamer switches between an open and a closed hairpin shape in the absence and in the presence of its cognate ligand, respectively. In the closed form the aptaswitch is recognized by another hairpin named aptakiss through kissing interaction. The aptakiss does not bind to the open aptaswitch. Consequently the aptakiss-aptaswitch complex signals the presence of the target. See paper NOVAswitch Kissing interactions are used to perform the selection in the Novaptech NOVAswitch procedure. Selection is carried out against free molecules in solution. The selected candidates are functional aptaswitches that can be integrated into biosensors. Learn about our R&#038;D programme for rapid &#038; multiplex testing Aptaswitch-based assays Rapid tests Aptamer lateral flow assays Environment &amp; food safety monitoring Detection of a drug in biological fluids They support our R&#038;D Any question ? Just ask us ! Any question about selection service or assay development ? Please fill in the form below with relevant details for helping us providing an informative answer. Telephone call can be arranged. NDA can be signed, would you wish so. We will answer you as quickly as possible (generally less than 2 working days). Contact us Your scientific contact : Jean-Jacques Toulm\u00e9, PhD, CSO<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Novatech structure switching aptamers - Novaptech<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/novaptech.com\/fr\/second-generation-aptamers-selkiss-aptaswitch\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Novatech structure switching aptamers - Novaptech\" \/>\n<meta property=\"og:description\" content=\"Novaptech structure-switching aptamers Novaptech Aptaswich &#038; NOVAswitch technology Aptamers are known to generally undergo a conformational change upon binding to their ligand. This can be exploited for signaling the presence of the target. The structural change is then associated to a signal (fluorescence energy transfer for instance). This can be deliberately exploited for the design of aptamer-based biosensors. Tell us about your assay Aptaswitch Novaptech structure switching aptamers take advantage of so-called kissing interactions. Loop-loop or \u201ckissing\u201d complexes involve the formation of a short double-strand between complementary apical loops of nucleic acid hairpins. The aptamer switches between an open and a closed hairpin shape in the absence and in the presence of its cognate ligand, respectively. In the closed form the aptaswitch is recognized by another hairpin named aptakiss through kissing interaction. The aptakiss does not bind to the open aptaswitch. Consequently the aptakiss-aptaswitch complex signals the presence of the target. See paper NOVAswitch Kissing interactions are used to perform the selection in the Novaptech NOVAswitch procedure. Selection is carried out against free molecules in solution. The selected candidates are functional aptaswitches that can be integrated into biosensors. Learn about our R&#038;D programme for rapid &#038; multiplex testing Aptaswitch-based assays Rapid tests Aptamer lateral flow assays Environment &amp; food safety monitoring Detection of a drug in biological fluids They support our R&#038;D Any question ? Just ask us ! Any question about selection service or assay development ? Please fill in the form below with relevant details for helping us providing an informative answer. Telephone call can be arranged. NDA can be signed, would you wish so. We will answer you as quickly as possible (generally less than 2 working days). 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This can be exploited for signaling the presence of the target. The structural change is then associated to a signal (fluorescence energy transfer for instance). This can be deliberately exploited for the design of aptamer-based biosensors. Tell us about your assay Aptaswitch Novaptech structure switching aptamers take advantage of so-called kissing interactions. Loop-loop or \u201ckissing\u201d complexes involve the formation of a short double-strand between complementary apical loops of nucleic acid hairpins. The aptamer switches between an open and a closed hairpin shape in the absence and in the presence of its cognate ligand, respectively. In the closed form the aptaswitch is recognized by another hairpin named aptakiss through kissing interaction. The aptakiss does not bind to the open aptaswitch. Consequently the aptakiss-aptaswitch complex signals the presence of the target. See paper NOVAswitch Kissing interactions are used to perform the selection in the Novaptech NOVAswitch procedure. Selection is carried out against free molecules in solution. The selected candidates are functional aptaswitches that can be integrated into biosensors. Learn about our R&#038;D programme for rapid &#038; multiplex testing Aptaswitch-based assays Rapid tests Aptamer lateral flow assays Environment &amp; food safety monitoring Detection of a drug in biological fluids They support our R&#038;D Any question ? Just ask us ! Any question about selection service or assay development ? Please fill in the form below with relevant details for helping us providing an informative answer. Telephone call can be arranged. NDA can be signed, would you wish so. We will answer you as quickly as possible (generally less than 2 working days). 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