{"id":3784,"date":"2025-02-28T13:37:45","date_gmt":"2025-02-28T13:37:45","guid":{"rendered":"https:\/\/novaptech.com\/?page_id=3784"},"modified":"2025-06-30T13:08:43","modified_gmt":"2025-06-30T13:08:43","slug":"publications","status":"publish","type":"page","link":"https:\/\/novaptech.com\/fr\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"
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Publications
Applications diverses des aptam\u00e8res<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Au cours des derni\u00e8res ann\u00e9es, Novaptech a d\u00e9velopp\u00e9 des aptam\u00e8res contre un large \u00e9ventail de cibles pour diverses applications dans les domaines de la sant\u00e9 et des sciences de la vie, des cosm\u00e9tiques, de l'agroalimentaire et des sciences de l'environnement.<\/p>

Ci-dessous, une s\u00e9lection de publications r\u00e9dig\u00e9es par J.-J. Toulm\u00e9, directeur scientifique de Novaptech.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Aptam\u00e8res - Sant\u00e9 et Sciences de la Vie<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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2025 - Livraison cibl\u00e9e \u00e0 l'aide d'aptam\u00e8res <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a><\/span><\/strong><\/h4>

Aptamer-conjugated gold nanoparticles enable oligonucleotide delivery into muscle stem cells to promote regeneration of dystrophic muscles<\/strong><\/span><\/a><\/h4>
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Francesco Millozzi, Paula Mil\u00e1n-Rois, Arghya Sett, Giovanni Delli Carpini, Marco De Bardi, Miguel Gisbert-Garzar\u00e1n, Martina Sandon\u00e0, Ciro Rodr\u00edguez-D\u00edaz, Mario Mart\u00ednez-Mingo, Irene Pardo, Federica Esposito, Maria Teresa Viscomi, Marina Bouch\u00e9, Ornella Parolini, Valentina Saccone, Jean-Jacques Toulm\u00e9, \u00c1lvaro Somoza & Daniela Palacios<\/span><\/p>

Mots cl\u00e9s : cellules souches musculaires, dystrophie de Duchenne, nanoparticules d\u2019or, microARN, r\u00e9g\u00e9n\u00e9ration<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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2016 - Aptam\u00e8re pour l'imagerie tumorale <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a><\/span><\/strong><\/h4>

Ex Vivo and In Vivo<\/em> Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas<\/span><\/strong><\/a><\/h4>
\u00a0<\/h6>

David Kryza , Fr\u00e9d\u00e9ric Debordeaux, Laurent Az\u00e9ma, Aref Hassan, Olivier Paurelle, J\u00fcrgen Schulz, Catherine Savona-Baron, Elsa Charignon, Pauline Bonazza, Jacqueline Taleb, Philippe Fernandez, Marc Janier , Jean Jacques Toulm\u00e9<\/span><\/p>

Mots-cl\u00e9s : Matrice M\u00e9talloprot\u00e9inase-9, aptam\u00e8re, imagerie tumorale, m\u00e9lanome, sonde radiomarqu\u00e9e, fluorescence, scintigraphie<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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2017 - Aptam\u00e8re pour la d\u00e9tection quantitative de m\u00e9dicament <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a><\/strong><\/span>A malachite green light-up aptasensor for the detection of theophylline<\/span><\/strong><\/a><\/h4>
\u00a0<\/h6>

Arghya Sett, L. Zara, \u00c9. Dausse, J. Toulm\u00e9<\/span><\/p>

Mots cl\u00e9s : biocapteur, aptam\u00e8re, fluorescence, th\u00e9ophylline, malachite green, aptasenseur<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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2017 - Aptam\u00e8re pour la d\u00e9tection quantitative d'un m\u00e9tabolite <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a><\/strong><\/span><\/h4>

A colorimetric nanosensor based on a selective target-responsive aptamer kissing complex<\/span><\/strong><\/a><\/h4>
\u00a0<\/h6>

Goux, E. Dausse, V. Guieu,\u00a0\u00a0 L. Az\u00e9ma\u00a0 G. Durand\u00a0 M. Henry\u00a0 L. Choisnard\u00a0\u00a0 J.-J. Toulm\u00e9\u00a0\u00a0 C. Raveleta\u00a0 and\u00a0 E. Peyrin<\/span><\/p>

Mots cl\u00e9s : aptasenseur colorim\u00e9trique, nanoparticules d\u2019or, kissing loop, agr\u00e9gation des nanoparticules, d\u00e9tection de petits analytes<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Aptam\u00e8res - Cosm\u00e9tique<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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2021 - Inhibition des aptam\u00e8res sur des k\u00e9ratinocytes humains <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"Study of a G-quadruplex aptamer inhibiting MMP-9 on human keratinocytes and on a 3D reconstructed human skin model<\/span><\/strong><\/h4>
Robin Kurfurst, Olivier Jeanneton, Isabelle Lorthois, Am\u00e9lie Th\u00e9pot, Morgan dos Santos<\/span><\/div>
October 2021; IFSCC Conference 2021, Mexico<\/span><\/div>
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Mots-cl\u00e9s : Matrice M\u00e9talloprot\u00e9inase-9, aptam\u00e8re, SELEX, vieillissement cutan\u00e9, d\u00e9gradation de la matrice extracellulaire, inhibition des Matrices M\u00e9talloprot\u00e9ases, mod\u00e8le de peau 3D, G-quadruplex<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Aptam\u00e8res - Agroalimentaire, environnement<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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2024 - Aptam\u00e8re pour la d\u00e9tection des fongicides <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a>Engineering optical aptasensors for the detection of fungicides<\/a><\/span><\/span><\/strong><\/h4>\n
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Petra Ivaskovic, Am\u00e9lie Florent, Hubert Debreyne, Jean Jacques Toulm\u00e9<\/span><\/div>\n
Juin 2024; Journ\u00e9es scientifiques du GDR ChemBio 2024, Bordeaux<\/span><\/div>\n
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Mots cl\u00e9s : fongicides, agriculture, aptam\u00e8res, d\u00e9tection quantitative, temps r\u00e9el, fluorescence, biosenseur optique\u00a0<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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2024 - Aptam\u00e8re pour la d\u00e9tection des antibiotiques <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a>Development of aptasensors for antibiotic monitoring<\/span><\/a><\/span><\/strong><\/h4>
\u00a0<\/div>
Hubert Debreyne, Petra Ivaskovic, C\u00e9lia Gutierrez, Pauline Duboeuf, Jean Jacques Toulm\u00e9<\/span><\/div>
2024; Internal use<\/span><\/div>
\u00a0<\/div>

Mots cl\u00e9s : antibiotiques, s\u00e9curit\u00e9 alimentaire, aptam\u00e8res, d\u00e9tection quantitative, temps r\u00e9el, fluorescence, biosenseur optique\u00a0<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Aptam\u00e8res - Biocapteurs<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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2015 - Test de type sandwich avec 2 aptam\u00e8res <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a><\/strong><\/span><\/h4>

Design of a dual aptamer-based recognition strategy for human matrix metalloproteinase 9 protein by piezoelectric biosensors<\/strong><\/span><\/a><\/h4>
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Scarano, E. Dausse, F. Crispo, J.-J. Toulm\u00e9, M. Minunni<\/span><\/div>
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Mots-cl\u00e9s : M\u00e9talloprot\u00e9inase de matrice-9<\/em>, biosenseur \u00e0 base d\u2019aptam\u00e8res, d\u00e9tection pi\u00e9zo\u00e9lectrique, essai sans marquage, neuroinflammation, maladie cardiovasculaire, biomarqueur s\u00e9rique<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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2016 - Essai enzymatique coupl\u00e9 \u00e0 un aptam\u00e8re <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a><\/h4>

EL<\/span><\/a><\/span><\/strong>AKCA: Enzyme-Linked Aptamer Kissing Complex Assay as a Small Molecule Sensing Platform<\/span><\/a><\/span><\/strong><\/h4>
\u00a0<\/div>
Benoit Chovelon, Guillaume Durand, Eric Dausse, Jean-Jacques Toulm\u00e9, Patrice Faure, Eric Peyrin, Corinne Ravelet<\/span><\/div>
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Mots-cl\u00e9s : essai \u00e0 base d'aptam\u00e8res, d\u00e9tection colorim\u00e9trique, d\u00e9tection de petites mol\u00e9cules, \u00e9pingle \u00e0 cheveux ARN, biocapteur, th\u00e9ophylline, ad\u00e9nosine, outil diagnostique.<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Aptam\u00e8res - Biomat\u00e9riaux, Nanotechnologie<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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2015 - Aptam\u00e8re - D\u00e9tection d'une mol\u00e9cule <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a><\/span><\/strong><\/h4>

Single-molecule observations of RNA-RNA kissing interactions in a DNA nanostructure<\/span><\/a>
<\/span><\/strong><\/h4>
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Yosuke Takeuchi , Masayuki Endo, Yuki Suzuki, Kumi Hidaka, Guillaume Durand, Eric Dausse, Jean-Jacques Toulm\u00e9, Hiroshi Sugiyama<\/span><\/div>
\u00a0<\/div>

Mots-cl\u00e9s : nanostructures d'ARN, interrupteur mol\u00e9culaire, aptam\u00e8re, d\u00e9tection du GTP, origami ADN, analyse monocellulaire, interaction sensible au ligand.<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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2017 - Aptam\u00e8re - Composant de base nanoscaffold <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a><\/span><\/span><\/h4>

Triggering nucleic acid nanostructure assembly by conditional kissing interactions <\/strong><\/span><\/span><\/a><\/h4>

Laurent Az\u00e9ma,\u00a0 Servane Bonnet-Salomon,\u00a0 Masayuki Endo,\u00a0 Yosuke Takeuchi, Guillaume Durand,\u00a0\u00a0 Tomoko Emura,\u00a0\u00a0 Kumi Hidaka,\u00a0\u00a0 Eric Dausse,\u00a0 Hiroshi Sugiyama, Jean-Jacques Toulm\u00e9<\/p><\/div>

Mots-cl\u00e9s : nanostructures d'acides nucl\u00e9iques, aptaswitch, aptam\u00e8re \u00e0 structure modul\u00e9e, assemblage sensible au ligand, nanorods d'oligonucl\u00e9otides, d\u00e9tection de l'ad\u00e9nosine<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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2012 - Aptam\u00e8re - Ligand enantiosp\u00e9cifique <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\"\"<\/a>\u00a0Deciphering Aromatic Oligoamide Foldamer\u2013DNA Interactions<\/span><\/a><\/span><\/span><\/strong><\/h4>
\u00a0<\/div>

Laurence Delauri\u00e8re, Dr. Zeyuan Dong, Dr. Katta Laxmi-Reddy, Dr. Fr\u00e9d\u00e9ric Godde, Dr. Jean-Jacques Toulm\u00e9, Dr. Ivan Huc<\/span><\/p><\/div>

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Mots-cl\u00e9s: foldamers, G-quadruplexes, int\u00e9ractions s\u00e9lectives, SELEX<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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D'autres publications peuvent \u00eatre consult\u00e9es sur Pubmed<\/a>.<\/span> Pour plus d'informations, merci de nous contacter<\/span><\/a>.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Votre contact scientifique :<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Jean-Jacques Toulm\u00e9, PhD, CSO<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Selected publicationsdiverse applications of aptamers Over the last years Novaptech developed aptamers against a wide range of targets for diverse applications in health and life sciences, cosmetics, agri-food and environmental sciences. Below is a selection of publications authored by J.-J. Toulm\u00e9, Novaptech CSO. Aptamers – Health and Life Sciences 2025 – Aptamer – guided delivery Aptamer-conjugated gold nanoparticles enable oligonucleotide delivery into muscle stem cells to promote regeneration of dystrophic muscles \u00a0 \u00a0 Francesco Millozzi, Paula Mil\u00e1n-Rois, Arghya Sett, Giovanni Delli Carpini, Marco De Bardi, Miguel Gisbert-Garzar\u00e1n, Martina Sandon\u00e0, Ciro Rodr\u00edguez-D\u00edaz, Mario Mart\u00ednez-Mingo, Irene Pardo, Federica Esposito, Maria Teresa Viscomi, Marina Bouch\u00e9, Ornella Parolini, Valentina Saccone, Jean-Jacques Toulm\u00e9, \u00c1lvaro Somoza & Daniela Palacios Keywords: muscle stem cells, Duchenne dystrophy, gold nanoparticles, microRNA, regeneration 2016 – Aptamer for imaging tumors Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas \u00a0 David Kryza , Fr\u00e9d\u00e9ric Debordeaux, Laurent Az\u00e9ma, Aref Hassan, Olivier Paurelle, J\u00fcrgen Schulz, Catherine Savona-Baron, Elsa Charignon, Pauline Bonazza, Jacqueline Taleb, Philippe Fernandez, Marc Janier , Jean Jacques Toulm\u00e9 Keywords: Matrix Metalloproteinase-9, aptamer, tumor imaging, melanoma, radiolabeled probe, fluorescence, scintigraphy 2017 – Aptamer for the quantitative detection of a drug A malachite green light-up aptasensor for the detection of theophylline \u00a0 Arghya Sett, L. Zara, \u00c9. Dausse, J. Toulm\u00e9 Keywords: biosensor, aptamer, fluorescence, theophylline, malachite green, aptasensor 2017 – Aptamer for the quantitative detection of a metabolite A colorimetric nanosensor based on a selective target-responsive aptamer kissing complex \u00a0 Goux, E. Dausse, V. Guieu,\u00a0\u00a0 L. Az\u00e9ma\u00a0 G. Durand\u00a0 M. Henry\u00a0 L. Choisnard\u00a0\u00a0 J.-J. Toulm\u00e9\u00a0\u00a0 C. Raveleta\u00a0 and\u00a0 E. Peyrin Keywords: colorimetric aptasensor, gold nanoparticles, kissing loop, nanoparticle aggregation, small analyte detection Aptamer-conjugated gold nanoparticles enable oligonucleotide delivery into muscle stem cells to promote regeneration of dystrophic muscles \u00a0 \u00a0 Francesco Millozzi, Paula Mil\u00e1n-Rois, Arghya Sett, Giovanni Delli Carpini, Marco De Bardi, Miguel Gisbert-Garzar\u00e1n, Martina Sandon\u00e0, Ciro Rodr\u00edguez-D\u00edaz, Mario Mart\u00ednez-Mingo, Irene Pardo, Federica Esposito, Maria Teresa Viscomi, Marina Bouch\u00e9, Ornella Parolini, Valentina Saccone, Jean-Jacques Toulm\u00e9, \u00c1lvaro Somoza & Daniela Palacios Keywords: muscle stem cells, Duchenne dystrophy, gold nanoparticles, microRNA, regeneration Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas \u00a0 David Kryza , Fr\u00e9d\u00e9ric Debordeaux, Laurent Az\u00e9ma, Aref Hassan, Olivier Paurelle, J\u00fcrgen Schulz, Catherine Savona-Baron, Elsa Charignon, Pauline Bonazza, Jacqueline Taleb, Philippe Fernandez, Marc Janier , Jean Jacques Toulm\u00e9 Keywords: Matrix Metalloproteinase-9, aptamer, tumor imaging, melanoma, radiolabeled probe, fluorescence, scintigraphy A malachite green light-up aptasensor for the detection of theophylline \u00a0 Arghya Sett, L. Zara, \u00c9. Dausse, J. Toulm\u00e9 Keywords: biosensor, aptamer, fluorescence, theophylline, malachite green, aptasensor A colorimetric nanosensor based on a selective target-responsive aptamer kissing complex \u00a0 Goux, E. Dausse, V. Guieu,\u00a0\u00a0 L. Az\u00e9ma\u00a0 G. Durand\u00a0 M. Henry\u00a0 L. Choisnard\u00a0\u00a0 J.-J. Toulm\u00e9\u00a0\u00a0 C. Raveleta\u00a0 and\u00a0 E. Peyrin Keywords: colorimetric aptasensor, gold nanoparticles, kissing loop, nanoparticle aggregation, small analyte detection Aptamers – Cosmetics 2021 – Inhibitory aptamer in human keratinocytes Study of a G-quadruplex aptamer inhibiting MMP-9 on human keratinocytes and on a 3D reconstructed human skin model Robin Kurfurst, Olivier Jeanneton, Isabelle Lorthois, Am\u00e9lie Th\u00e9pot, Morgan dos SantosOctober 2021; IFSCC Conference 2021, Mexico\u00a0 Keywords: Matrix Metalloproteinase-9, aptamer, SELEX, skin aging, extracellular matrix degradation, Matrix Metalloproteinases inhibition, 3D skin model, G quadruplex Study of a G-quadruplex aptamer inhibiting MMP-9 on human keratinocytes and on a 3D reconstructed human skin model Robin Kurfurst, Olivier Jeanneton, Isabelle Lorthois, Am\u00e9lie Th\u00e9pot, Morgan dos SantosOctober 2021; IFSCC Conference 2021, Mexico\u00a0 Keywords: Matrix Metalloproteinase-9, aptamer, SELEX, skin aging, extracellular matrix degradation, Matrix Metalloproteinases inhibition, 3D skin model, G quadruplex Aptamers \u2013 Agri-food, environment 2024 – Aptamer for fungicide detection Engineering optical aptasensors for the detection of fungicides Petra Ivaskovic, Am\u00e9lie Florent, Hubert Debreyne, Jean Jacques Toulm\u00e9 Juin 2024; Journ\u00e9es scientifiques du GDR ChemBio 2024, Bordeaux Keywords: fungicides, agriculture, aptamers, real time, quantitative detection, fluorescence, optical biosensor\u00a0 2024 – Aptamer for antibiotic detection Development of aptasensors for antibiotic monitoring \u00a0Hubert Debreyne, Petra Ivaskovic, C\u00e9lia Gutierrez, Pauline Duboeuf, Jean Jacques Toulm\u00e92024; Internal use\u00a0 Keywords: antibiotics, food safety, aptamers, real time, quantitative detection, fluorescence, optical biosensor\u00a0 Engineering optical aptasensors for the detection of fungicides Petra Ivaskovic, Am\u00e9lie Florent, Hubert Debreyne, Jean Jacques Toulm\u00e9 Juin 2024; Journ\u00e9es scientifiques du GDR ChemBio 2024, Bordeaux Keywords: fungicides, agriculture, aptamers, real time, quantitative detection, fluorescence, optical biosensor\u00a0 Development of aptasensors for antibiotic monitoring \u00a0Hubert Debreyne, Petra Ivaskovic, C\u00e9lia Gutierrez, Pauline Duboeuf, Jean Jacques Toulm\u00e92024; Internal use\u00a0 Keywords: antibiotics, food safety, aptamers, real time, quantitative detection, fluorescence, optical biosensor\u00a0 Aptamers \u2013 Biosensors 2015 – Sandwich assay with 2 aptamers Design of a dual aptamer-based recognition strategy for human matrix metalloproteinase 9 protein by piezoelectric biosensors \u00a0Scarano, E. Dausse, F. Crispo, J.-J. Toulm\u00e9, M. Minunni\u00a0 Keywords: Matrix Metalloproteinase-9, aptamer biosensor, piezoelectric detection, label-free assay, neuroinflammation, cardiovascular disease, serum biomarker 2016 – Aptamer – Enzyme linked assay ELAKCA: Enzyme-Linked Aptamer Kissing Complex Assay as a Small Molecule Sensing Platform \u00a0Benoit Chovelon, Guillaume Durand, Eric Dausse, Jean-Jacques Toulm\u00e9, Patrice Faure, Eric Peyrin, Corinne Ravelet\u00a0 Keywords: aptamer-based assay, colorimetric detection, small molecule sensing, RNA hairpin, biosensor, theophylline, adenosine, diagnostic tool. Design of a dual aptamer-based recognition strategy for human matrix metalloproteinase 9 protein by piezoelectric biosensors \u00a0Scarano, E. Dausse, F. Crispo, J.-J. Toulm\u00e9, M. Minunni\u00a0 Keywords: Matrix Metalloproteinase-9, aptamer biosensor, piezoelectric detection, label-free assay, neuroinflammation, cardiovascular disease, serum biomarker ELAKCA: Enzyme-Linked Aptamer Kissing Complex Assay as a Small Molecule Sensing Platform \u00a0Benoit Chovelon, Guillaume Durand, Eric Dausse, Jean-Jacques Toulm\u00e9, Patrice Faure, Eric Peyrin, Corinne Ravelet\u00a0 Keywords: aptamer-based assay, colorimetric detection, small molecule sensing, RNA hairpin, biosensor, theophylline, adenosine, diagnostic tool. Aptamers \u2013 Biomaterials, Nanotechnology 2015 – Aptamer – Single molecule detection Single-molecule observations of RNA-RNA kissing interactions in a DNA nanostructure \u00a0\u00a0\u00a0Yosuke Takeuchi , Masayuki Endo, Yuki Suzuki, Kumi Hidaka, Guillaume Durand, Eric Dausse, Jean-Jacques Toulm\u00e9, Hiroshi Sugiyama\u00a0 Keywords: RNA nanostructures, molecular switch, aptamer, GTP sensing, DNA origami, single-molecule analysis, ligand-responsive interaction 2017 – Aptamer – Building block for nanoscaffold Triggering nucleic acid nanostructure assembly by conditional kissing interactions Laurent Az\u00e9ma,\u00a0 Servane Bonnet-Salomon,\u00a0 Masayuki Endo,\u00a0 Yosuke Takeuchi, Guillaume Durand,\u00a0\u00a0 Tomoko Emura,\u00a0\u00a0<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-3784","page","type-page","status-publish","hentry"],"yoast_head":"\nPublications - 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